Document Detail

Atrial fibrillation and chronic kidney disease.
MedLine Citation:
PMID:  23190235     Owner:  NLM     Status:  In-Data-Review    
To the Editor: Olesen et al. (Aug. 16 issue)(1) report that in their study, warfarin treatment was associated with a decreased risk of thromboembolic events among patients requiring renal-replacement therapy. In contrast, three large registry studies concluded that in patients with atrial fibrillation who were undergoing hemodialysis, warfarin was associated with an increased risk of stroke.(2)-(4) In addition, generally in patients who are receiving hemodialysis and warfarin, the risks of bleeding, cardiovascular calcifications, and calciphylaxis markedly increase. We therefore have argued against the use of warfarin in patients with atrial fibrillation who are receiving hemodialysis.(5) There are important limitations . . .
Georg Schlieper; Thilo Krüger; Jürgen Floege
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  367     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2157-9     Citation Subset:  AIM; IM    
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