Document Detail

Atrial fibrillation and cardiembolic stroke. Treatment and issue in acute phase.
MedLine Citation:
PMID:  22277457     Owner:  NLM     Status:  In-Data-Review    
In addition to the general treatment, rt-PA intravenous thrombolysis, intraarterial thrombolysis, brain protecting therapy with edaravone, glycerol treatment against brain edema, and immediate anticoagulant therapy should be considered in acute phase of cardioembolic stroke. The rt-PA intravenous thrombolysis within three hours of onset is recommended in acute stroke patients who meet criteria for the therapy. Because the efficacy of immediate anticoagulation in acute cardioembolic stroke has not been established yet, it depends on balance of risk and benefit in each patient whether immediate anticoagulant therapy should be commenced or not. When we start anticoagulation with warfarin, heparin which has rapid action should be administered at the same time until PT-INR increases into therapeutic range to avoid acute recurrent stroke. However when we start with dabigatran which has rapid action, heparin is usually not required.
Masahiro Yasaka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rinshō shinkeigaku = Clinical neurology     Volume:  51     ISSN:  0009-918X     ISO Abbreviation:  Rinsho Shinkeigaku     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2012-01-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417466     Medline TA:  Rinsho Shinkeigaku     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1001-3     Citation Subset:  IM    
Cerebrovascular Medicine, Kyushu Medical Center.
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