Document Detail

Atrial enlargement in symptomatic heart block patients with preserved left ventricular function: Possibly related to atrioventricular dyssynchrony.
MedLine Citation:
PMID:  19942307     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Right ventricular apical pacing may possibly induce atrial dilatation as a consequence of atrioventricular dyssynchrony. However, atrial enlargement associated with atrioventricular dyssynchrony due to atrioventricular block has never been studied.
METHODS: This case-control survey involved 90 patients with symptomatic atrioventricular block [29 patients with Mobitz type 2 atrioventricular block, 22 patients with high degree of atrioventricular block and 39 patients with complete atrioventricular block]. The control group comprised 54 age- and sex-matched patients with sick sinus syndrome and intact intrinsic atrioventricular conduction. The M-mode measurements were obtained before implant and the left and right atrial areas were measured by planimetry.
RESULTS: The peri-implant right atrial area (17.4±3.7 vs. 15.3±3.4cm(2), p=0.002), left atrial area (24.9±4.2 vs. 21.0±3.7cm(2), p<0.001) and left atrial diameter (36.4±5.5 vs. 33.3±4.8mm, p=0.001) were significantly greater in atrioventricular block patients than in sick sinus syndrome patients. The two groups had similar left ventricular ejection fraction. The right atrial area (p=0.01) and left atrial area (p=0.006) remained significantly greater in atrioventricular block patients than in sick sinus syndrome patients after adjustments for age, gender, body surface area, left ventricular dimension and left ventricular ejection fraction in multiple logistic regression analysis.
CONCLUSIONS: Atrial enlargement occurs in patients with symptomatic atrioventricular block. This phenomenon is possibly related to atrioventricular dyssynchrony.
Yu-Sheng Lin; G Bih-Fang Guo; Yung-Lung Chen; Tzu-Hsien Tsai; Kuo-Li Pan; Wen-Hao Liu; Mien-Cheng Chen
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Publication Detail:
Type:  Journal Article     Date:  2009-11-26
Journal Detail:
Title:  International journal of cardiology     Volume:  148     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  280-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
Division of Cardiology, Chang Gung Memorial Hospital, Chiayi, Chang Gung Institute of Technology, Taiwan, ROC.
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