Document Detail


Atosiban and nifedipine in the suppression of pre-term labour: A comparative study.
MedLine Citation:
PMID:  23259877     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This is a retrospective study comparing the efficacy and safety of atosiban and nifedipine in the suppression of pre-term labour. A total of 75 patients were included in this study; 34 received atosiban and 41 received nifedipine. There were no statistically significant differences in the baseline characteristics for both groups. A total of 68.3% of women in the atosiban group remained undelivered at 7 days or more, compared with 64.7% in the nifedipine group, which was not statistically significant. Average birth weight, admission to the neonatal intensive care unit and mode of delivery were similar in both groups. However, the gestational age at delivery was significantly higher in the nifedipine group. We concluded that atosiban and nifedipine are effective in delaying delivery for 7 days or more in women presenting with pre-term labour. They have the same efficacy and associated minor side-effects. However, flushing, palpitation and hypotension were significantly higher in the nifedipine group.
Authors:
S S Saleh; M Q Al-Ramahi; F A Al Kazaleh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  33     ISSN:  1364-6893     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  43-5     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, Jordan University Hospital , Amman , Jordan.
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