Document Detail


Atopy in children with eczema.
MedLine Citation:
PMID:  20422327     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To explore the prevalence of common food and aeroallergens sensitization in early childhood skin diseases. and to compare the pattern of common food and aeroallergens sensitization before and after 6 months among infants with atopic dermatitis (AD).
METHODS: All skin prick tests (SPTs) performed on children pound18 months of age managed at the pediatric dermatology clinic of an university-affiliated teaching hospital over a 16-month period were examined.
RESULTS: There was generally no difference in the pattern of sensitization to common food and aeroallergens between AD patients and non-AD young children with miscellaneous dermatological or gastrointestinal conditions. Dust mites were the only common aeroallergens in these patients; whereas egg and peanuts were the common sensitizing food allergens. Cat and dog fur as aeroallergens, soy bean, orange and beef as food allergens were relatively uncommon among the studied subjects. In AD, infants pound 6 months were generally naive to aeroallergens but became sensitized to the D. Pteronyssinus in the next 12 months of age. 80% of these infants were not sensitized to cow's milk and none sensitized to soybean.
CONCLUSION: Atopic sensitization to common allergens was common in early childhood with or without AD. Majority of young infants were not sensitized to milk, and develop eczema before they show atopy to the milk or soy allergens.
Authors:
Kam-Lun Ellis Hon; Susanna Tsang; Ching-Yi Wong; Pui-Man Tse; Charles Wong; Wing-Hei Zion To; Chung-Mo Chow; Wai-San Fanny Ko; Ting-Fan Leung
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Publication Detail:
Type:  Journal Article     Date:  2010-03-19
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  77     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-21     Completed Date:  2011-03-03     Revised Date:  2011-10-16    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  519-22     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. ehon@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Animals
Arachis hypogaea / immunology
Chi-Square Distribution
Eczema / immunology*
Egg Hypersensitivity / immunology
Female
Food Hypersensitivity / immunology*
Humans
Infant
Infant, Newborn
Male
Mites / immunology*
Skin Tests
Comments/Corrections
Erratum In:
Indian J Pediatr. 2011 Sep;78(9):1161

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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