Document Detail


Atopic dermatitis: serum immunoglobulins and T-lymphocyte subpopulations.
MedLine Citation:
PMID:  1669572     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A group of patients with atopic dermatitis who attended the Allergy Outpatient Service of the Hermanos Ameijeiras Clinical Surgical Hospital from May, 1987 to May, 1988 were studied. The patients were assigned to 2 groups; the first one composed of 38 patients and the second one composed of 12 non-allergic, supposedly healthy subjects. Different tests were carried out for the quantification of total serum immunoglobulins (A, G, M, E) by means of the radial immunodiffusion method and the ELISA ultramicromethod. They were also submitted to quantification of lymphocyte subpopulations by means of the indirect immunofluorescence test with monoclonal antibodies, using Cuban antiserum prepared at the National Institute of Oncology and Radiobiology. In our study IgG and IgA values were within normal limits in patients, contrary to the statistically significant increase in IgM and IgE values. The relative values of total T-lymphocytes (anti-T3) and of the suppressor lymphocyte subpopulations decreased.
Authors:
A F Valdés Sánchez; A H Gómez Echevarría; G Lastra Alfonso
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología     Volume:  1     ISSN:  1018-9068     ISO Abbreviation:  J Investig Allergol Clin Immunol     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1994-02-22     Completed Date:  1994-02-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9107858     Medline TA:  J Investig Allergol Clin Immunol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  154-8     Citation Subset:  IM    
Affiliation:
Hermanos Ameijeiras Clinical Surgical Hospital, Havana, Cuba.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Dermatitis, Atopic / blood*,  immunology*
Humans
Immunoglobulin A / blood
Immunoglobulin E / blood
Immunoglobulin G / blood
Immunoglobulin M / blood
Immunoglobulins / blood*
Leukocyte Count
Middle Aged
T-Lymphocyte Subsets*
T-Lymphocytes, Regulatory
Chemical
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Immunoglobulins; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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