Document Detail


Atopic asthma caused by Candida albicans acid protease: case reports.
MedLine Citation:
PMID:  7695069     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two cases of atopic asthma caused by acid protease produced by Candida albicans are reported. Both patients had high levels of serum IgE antibodies against the acid protease and showed positive conjunctival and immediate bronchial responses when challenged with the protease. Significant histamine release was detected in both patients when their peripheral leukocytes were challenged with the protease antigen. These findings clearly showed that C. albicans acid protease is the causative allergen of atopic asthma.
Authors:
K Akiyama; T Shida; H Yasueda; H Mita; T Yamamoto; H Yamaguchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Allergy     Volume:  49     ISSN:  0105-4538     ISO Abbreviation:  Allergy     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-04-21     Completed Date:  1995-04-21     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  778-81     Citation Subset:  IM    
Affiliation:
National Sagamihara Hospital, Kanagawa, Japan.
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MeSH Terms
Descriptor/Qualifier:
Allergens / adverse effects*,  metabolism
Aspartic Acid Endopeptidases / adverse effects*,  metabolism
Asthma / blood,  diagnosis,  immunology*
Bronchial Provocation Tests
Candida albicans / enzymology
Female
Humans
Hypersensitivity, Immediate / blood,  diagnosis,  immunology
Immunoglobulin E / blood
Middle Aged
Skin Tests
Chemical
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E; EC 3.4.23.-/Aspartic Acid Endopeptidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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