Document Detail


Atomic force microscopy of Plasmodium-infected red blood cells: detecting and localizing single molecular recognition events.
MedLine Citation:
PMID:  22990787     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Atomic Force Microscopy (AFM) is a powerful tool for exploring the interaction between ligands and receptors, as well as their exact locations on the red cell surface. Here we discuss current and future applications for AFM based single-molecule force spectroscopy to study adhesion of Plasmodium-infected red blood cells. A protocol is provided for simultaneous topography and recognition imaging of the surface of Plasmodium falciparum-infected cells using CD36 functionalized tips.
Authors:
Ang Li; Laurent Rénia; Chwee Teck Lim; Bruce Russell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  923     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2013  
Date Detail:
Created Date:  2012-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-305     Citation Subset:  IM    
Affiliation:
Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
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