Document Detail

Atom- and Step-Economical Pathway to Chiral Benzobicyclo[2.2.2]octenones through Carbon-Carbon Bond Cleavage.
MedLine Citation:
PMID:  22287511     Owner:  NLM     Status:  Publisher    
In the nick of time: A nickel-catalyzed asymmetric intramolecular alkene insertion reaction into cyclobutanones (1) has been developed. The reaction significantly reduces the number of steps required for the synthesis of chiral benzobicyclo[2.2.2]octenones (2).
Lantao Liu; Naoki Ishida; Masahiro Murakami
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-27
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  -     ISSN:  1521-3773     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, (Japan)
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