Document Detail

Atlanto-axial subluxation in patients with seronegative spondylarthritis.
MedLine Citation:
PMID:  3495855     Owner:  NLM     Status:  MEDLINE    
Two patients with seronegative HLA-B27-connected spondylarthropathy, associated in one case with psoriasis and in the other with Reiter's disease, who had atlanto-axial subluxation (AAS) are reported. The AAS caused muscle weakness and intractable occipito-cervical pain. Both patients were treated operatively with a Gallie type C1-C2 fusion. The symptoms subsided following surgery and the patients remained free of cervical spine discomfort. The report also indicates that the rarer variants of the HLA-B27 associated chronic seronegative spondylarthropathies may cause AAS complicated by neurological symptoms and that the disorder is amenable to surgical intervention.
S Santavirta; P Slätis; J Sandelin; C Lindqvist; Y T Konttinen
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Rheumatology international     Volume:  7     ISSN:  0172-8172     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  1987  
Date Detail:
Created Date:  1987-07-08     Completed Date:  1987-07-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  43-6     Citation Subset:  IM    
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MeSH Terms
Arthritis / complications*,  genetics
Arthritis, Reactive / complications*
Atlanto-Axial Joint / injuries*
Dislocations / etiology*,  surgery
HLA Antigens / genetics
HLA-B27 Antigen
Pain, Intractable / etiology
Psoriasis / complications
Spinal Diseases / complications*,  genetics
Reg. No./Substance:
0/HLA Antigens; 0/HLA-B27 Antigen

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