Document Detail

Atherosclerotic lesion of the circle of Willis: its study applying an atherometric system using multivariate statistical techniques.
MedLine Citation:
PMID:  1914471     Owner:  NLM     Status:  MEDLINE    
In 2043 autopsies divided into the high (HAG) and low (LAG) atherosclerosis group a set of variables of a new atherometric system (AS) was used to characterize the atherosclerotic lesion (AL) in the circle of Willis arteries: fatty streaks (X), fibrous plaques (Y), severe plaques (Z), index of stenosis (P) and index of benignity (B). Principal component analysis identified a first component of severity (Y, P and Z) and a second component of benignity (X and B). Fibrous plaques play the main role in the severity of AL in the circle of Willis. The new AS proved its usefulness in characterizing the state of AL, whereas discriminant analysis and AS distinguished between the HAG and the LAG. The classification was correct in 74.5% and 76.5% when using three (X, Y, Z) and five (X, Y, Z, P, B) variables, respectively.
J E Fernández-Britto; J Bacallao; P V Carlevaro; A S Koch; H Guski; R Campos; L Falcón
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  33     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1991  
Date Detail:
Created Date:  1991-11-13     Completed Date:  1991-11-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  188-96     Citation Subset:  IM    
Higher Institute of Medical Sciences, Havana, Cuba.
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MeSH Terms
Arteriosclerosis / pathology
Circle of Willis / pathology*
Discriminant Analysis
Intracranial Arteriosclerosis / pathology*
Numerical Analysis, Computer-Assisted

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