Document Detail

Atherosclerotic cardiovascular disease in systemic lupus erythematosus: the Beer Sheva experience.
MedLine Citation:
PMID:  18300571     Owner:  NLM     Status:  MEDLINE    
Atherosclerotic disease is common in systemic lupus erythematosus and is the result of multiple pathogenic mechanisms that include traditional risk factors as well as SLE-related factors. Endothelial dysfunction and arterial stiffness contribute significantly to the atherogenic process. Dobutamine stress echocardiogram has not been shown to detect subclinical coronary artery disease; however, the high percentage of left ventricular outflow gradient requires further evaluation and follows-up studies.
Mahmoud Abu-Shakra; Shlomi Codish; Lior Zeller; Talya Wolak; Shaul Sukenik
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  10     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  43-4     Citation Subset:  IM    
Rheumatic Diseases Unit and Lupus Clinic, Soroka Medical Center, Beer Sheva, Israel.
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MeSH Terms
Atherosclerosis / physiopathology*
Coronary Artery Disease / diagnosis
Endothelium, Vascular / physiopathology
Lupus Erythematosus, Systemic / physiopathology*
Mass Screening / methods
Tunica Intima / pathology
Tunica Media / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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