Document Detail

Atherosclerosis risk is higher in continuous ambulatory peritoneal dialysis patients than in hemodialysis patients.
MedLine Citation:
PMID:  11453874     Owner:  NLM     Status:  MEDLINE    
While it has been reported that myocardial infarction and cerebrovascular disease are more common in continuous ambulatory peritoneal dialysis (CAPD) patients than in hemodialysis patients, some studies have not supported these results. The aim of this study was to compare CAPD and hemodialysis patients with regard to atherosclerotic changes and to assess which factors might be responsible for atherosclerosis in dialysis patients. Group 1 consisted of 65 CAPD patients, and Group 2 consisted of 109 hemodialysis patients who were age-, gender-, and duration-of-dialysis-matched with CAPD patients. We used ultrasonographic measurement of carotid artery intima media thickness to identify atherosclerosis. Known risk factors for atherosclerosis including hypertension, smoking, serum levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol, lipoprotein (a) [Lp(a)], albumin, intact parathormone, fibrinogen, and C-reactive protein were determined in all patients. More atherosclerotic changes were seen in CAPD than in hemodialysis patients. Of all the atherosclerosis risk factors, only serum total cholesterol, LDL-C, and Lp(a) levels were significantly higher in patients on CAPD.
F N Ozdemir; G Güz; S Sezer; Z Arat; M Turan; M Haberal
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  25     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-16     Completed Date:  2001-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  448-52     Citation Subset:  IM    
Department of Nephrology, Baskent University Faculty of Medicine, Fevzi Cakmak Bulvari 10, Sokak No: 45, Bahçelievler, Ankara, 06490, Turkey.
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MeSH Terms
Arteriosclerosis / blood,  etiology*,  ultrasonography
Chi-Square Distribution
Lipids / blood
Middle Aged
Peritoneal Dialysis, Continuous Ambulatory / adverse effects*
Renal Dialysis / adverse effects*
Risk Factors
Reg. No./Substance:

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