Document Detail

Atherogenic dyslipidemia--a medical underwriter's iceberg.
MedLine Citation:
PMID:  20666105     Owner:  NLM     Status:  MEDLINE    
Life insurance medical underwriters assess cardiovascular risk by applying versions of cholesterol guidelines that were written in the early 1980s, when people were not obese, triglyceride levels were lower, and the low-density lipoprotein particles carried 95% of the cholesterol ester. Today in 2010, 30% of the population is obese, triglyceride levels are higher, HDL-C levels are lower, and LDL-P may carry as little as 60% of the circulating cholesterol ester. Applicants with cardiometabolic risk have an atherogenic dyslipidemia, which is characterized by a normal LDL-C, numerous small LDL-particles, mildly elevated triglycerides, and a depressed level of HDL--and a markedly increased risk of coronary artery disease. New and alternative lipid tests are available to help insurers better underwrite this new risk.
Robert Gleeson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of insurance medicine (New York, N.Y.)     Volume:  41     ISSN:  0743-6661     ISO Abbreviation:  J Insur Med     Publication Date:  2009  
Date Detail:
Created Date:  2010-07-29     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8401468     Medline TA:  J Insur Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  264-9     Citation Subset:  T    
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MeSH Terms
Coronary Artery Disease / blood,  etiology*
Dyslipidemias / blood,  complications,  diagnosis*
Insurance, Life*
Risk Assessment / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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