| Atherogenic dyslipidemia in patients with established coronary artery disease. | |
| | |
MedLine Citation:
|
PMID: 20675108 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND AND AIMS: Patients with stable coronary heart disease (CHD) and atherogenic dyslipidemia (AD) have a high-risk of recurrence and are those who derive most benefit from treatment with lipid-lowering agents. The aim of this study was to examine the prevalence of AD in patients with stable coronary heart disease and to investigate associated factors. METHODS: Cross-sectional study involving 7823 subjects admitted for a coronary event between 6 months and 10 years previously. AD was considered to be the concurrent presence of low HDL-cholesterol (<1.03 mmol/L [40 mg/dL] in males, <1.29 mmol/L [50 mg/dL] in females) and elevated triglycerides (≥1.7 mmol/L [150 mg/dL]). RESULTS: Mean age was 65.3 (10.1) years, 73.6% were males and 80.3% were receiving treatment with statins. Low HDL-cholesterol was observed in 26.3% of the participants, 39.7% had elevated triglyceride concentration and 13.0% had AD. The percentage of AD in patients with criteria for metabolic syndrome was 30.9%. Factors associated directly and independently with the presence of AD in the multivariate analysis were female sex, history of coronary syndrome without ST elevation or coronary revascularization, presence of atrial fibrillation, body mass index, LDL-cholesterol, systolic blood pressure and blood glucose levels, while age and glomerular filtration rate were significantly and inversely associated with AD. CONCLUSION: A significant proportion of patients with coronary disease could benefit from interventions aimed at increasing HDL-cholesterol and reducing triglycerides. |
| | |
Authors:
|
C Lahoz; J M Mostaza; S Tranche; R Martin-Jadraque; M T Mantilla; I López-Rodriguez; B Monteiro; M A Sanchez-Zamorano; M Taboada |
Related Documents
:
|
16998148 - Trans fatty acids and coronary heart disease. 1751258 - Ischemic heart disease, serum cholesterol, and apolipoproteins in capd. 17682928 - Statin therapy for vascular failure. 3055918 - Therapeutic control of hyperlipidemia in the prevention of coronary atherosclerosis: a ... 10219928 - Optimism and rehospitalization after coronary artery bypass graft surgery. 12813378 - Off-pump versus on-pump coronary bypass. comparison of patient characteristics and earl... |
Publication Detail:
|
Type: Journal Article Date: 2010-08-02 |
Journal Detail:
|
Title: Nutrition, metabolism, and cardiovascular diseases : NMCD Volume: 22 ISSN: 1590-3729 ISO Abbreviation: Nutr Metab Cardiovasc Dis Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9111474 Medline TA: Nutr Metab Cardiovasc Dis Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 103-8 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
|
Unidad de Arteriosclerosis, Hospital Carlos III, Sinesio Delgado 10, 28036 Madrid, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Red meat consumption and risk of heart failure in male physicians.
Next Document: Early development of essential fatty acid deficiency in rats: fat-free vs. hydrogenated coconut oil ...