| Atherogenic dyslipidemia: cardiovascular risk and dietary intervention. | |
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MedLine Citation:
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PMID: 20524075 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Atherogenic dyslipidemia comprises a triad of increased blood concentrations of small, dense low-density lipoprotein (LDL) particles, decreased high-density lipoprotein (HDL) particles, and increased triglycerides. A typical feature of obesity, the metabolic syndrome, insulin resistance, and type 2 diabetes mellitus, atherogenic dyslipidemia has emerged as an important risk factor for myocardial infarction and cardiovascular disease. A number of genes have now been linked to this pattern of lipoprotein changes. Low-carbohydrate diets appear to have beneficial lipoprotein effects in individuals with atherogenic dyslipidemia, compared to high-carbohydrate diets, whereas the content of total fat or saturated fat in the diet appears to have little effect. Achieving a better understanding of the genetic and dietary influences underlying atherogenic dyslipidemia may provide clues to improved interventions to reduce the risk of cardiovascular disease in high-risk individuals. |
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Authors:
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Kiran Musunuru |
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Publication Detail:
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Type: Journal Article Date: 2010-06-04 |
Journal Detail:
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Title: Lipids Volume: 45 ISSN: 1558-9307 ISO Abbreviation: Lipids Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0060450 Medline TA: Lipids Country: Germany |
Other Details:
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Languages: eng Pagination: 907-14 Citation Subset: IM |
Affiliation:
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Cardiology Division, Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, CPZN 5th floor, Boston, MA 02114, USA. kmusunuru@partners.org |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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