Document Detail


Atenolol versus amlodipine versus isosorbide-5-mononitrate on anginal symptoms in syndrome X.
MedLine Citation:
PMID:  10513787     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of a beta blocker (atenolol), a calcium antagonist (amlodipine), and a nitrate (isosorbide-5-mononitrate) on anginal symptoms in 10 patients with syndrome X were assessed in a crossover, double-blind, randomized trial. Only atenolol was found to significantly improve chest pain episodes, suggesting that it should be the preferred drug when starting pharmacologic treatment of patients with syndrome X.
Authors:
G A Lanza; G Colonna; V Pasceri; A Maseri
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The American journal of cardiology     Volume:  84     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-10-21     Completed Date:  1999-10-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  854-6, A8     Citation Subset:  AIM; IM    
Affiliation:
Istituto di Cardiologia Cardiologia, Universitá Cattolica, Roma, Italy. g.a.lanza@eudoramail.com
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use*
Amlodipine / therapeutic use*
Analysis of Variance
Atenolol / therapeutic use*
Cross-Over Studies
Double-Blind Method
Female
Humans
Isosorbide Dinitrate / therapeutic use*
Microvascular Angina / drug therapy*
Middle Aged
Statistics, Nonparametric
Treatment Outcome
Vasodilator Agents / therapeutic use*
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Vasodilator Agents; 29122-68-7/Atenolol; 87-33-2/Isosorbide Dinitrate; 88150-42-9/Amlodipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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