Document Detail

Atelectasis as a cause of postoperative fever: where is the clinical evidence?
MedLine Citation:
PMID:  21527508     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Atelectasis is considered to be the most common cause of early postoperative fever (EPF) but the existing evidence is contradictory. We sought to determine if atelectasis is associated with EPF by analyzing the relevant published evidence.
METHODS: We performed a systematic search in PubMed and Scopus databases to identify studies examining the association between atelectasis and EPF.
RESULTS: A total of eight studies, including 998 cardiac, abdominal, and maxillofacial surgery patients, were eligible for analysis. Only two studies specifically examined our question, and six additional articles reported sufficient data to be included. Only one study reported a significant association between postoperative atelectasis and fever, whereas the remaining studies indicated no such association. The performance of EPF as a diagnostic test for atelectasis was also assessed, and EPF performed poorly (pooled diagnostic OR, 1.40; 95% CI, 0.92-2.12). The significant heterogeneity among the studies precluded a formal metaanalysis.
CONCLUSION: The available evidence regarding the association of atelectasis and fever is scarce. We found no clinical evidence supporting the concept that atelectasis is associated with EPF. More so, there is no clear evidence that atelectasis causes fever at all. Large studies are needed to precisely evaluate the contribution of atelectasis in EPF.
Michael N Mavros; George C Velmahos; Matthew E Falagas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2011-04-28
Journal Detail:
Title:  Chest     Volume:  140     ISSN:  1931-3543     ISO Abbreviation:  Chest     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-04     Completed Date:  2011-10-13     Revised Date:  2012-02-08    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  418-24     Citation Subset:  AIM; IM    
Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece.
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MeSH Terms
Fever / etiology*
Postoperative Complications / etiology*
Pulmonary Atelectasis / complications*
Comment In:
Chest. 2012 Jan;141(1):274-5; author reply 275   [PMID:  22215840 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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