Document Detail

Ataxia caused by amiodarone in older people.
MedLine Citation:
PMID:  18385185     Owner:  NLM     Status:  MEDLINE    
Amiodarone is recommended for the cardioversion of atrial fibrillation and prevention of paroxysmal atrial fibrillation in patients with structural heart disease, coronary artery disease or left ventricular dysfunction. It has well-recognised side-effects on the skin, lungs, liver, thyroid and eyes. Neurological side-effects, including ataxia and neuropathy, also occur, and may be more prevalent in older patients. These side-effects are reversible after cessation of amiodarone. Monitoring of amiodarone therapy should include assessment of the central and peripheral nervous system especially in older patients.
J V Hindle; Amin Ibrahim; Radhakrishnan Ramaraj
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-04-02
Journal Detail:
Title:  Age and ageing     Volume:  37     ISSN:  1468-2834     ISO Abbreviation:  Age Ageing     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-05     Completed Date:  2008-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  England    
Other Details:
Languages:  eng     Pagination:  347-8     Citation Subset:  IM    
Department of Care of the Elderly, Llandudno Hospital, North West Wales NHS Trust, Llandudno, Conwy, LL30 1LB, UK.
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MeSH Terms
Aged, 80 and over
Amiodarone / administration & dosage,  adverse effects*,  therapeutic use
Anti-Arrhythmia Agents / administration & dosage,  adverse effects*,  therapeutic use
Ataxia / chemically induced*
Atrial Fibrillation / drug therapy
Dose-Response Relationship, Drug
Drug Administration Schedule
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 1951-25-3/Amiodarone

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