Document Detail

AtMYB4: a transcription factor general in the battle against UV.
MedLine Citation:
PMID:  11286899     Owner:  NLM     Status:  MEDLINE    
Mounting evidence indicates that members of the large family of plant MYB proteins are involved in the transcriptional regulation of an array of metabolic and developmental processes. Recently, the Arabidopsis thaliana MYB, AtMYB4, was shown to regulate the accumulation of the UV-protectant compound sinapoylmalate by repressing the transcription of the gene encoding the phenylpropanoid enzyme cinnamate 4-hydroxylase. AtMYB4 is thus a key regulator of phenylpropanoid pathway gene expression, and is the first example of a MYB protein that functions as a transcriptional repressor.
M R Hemm; K M Herrmann; C Chapple
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Trends in plant science     Volume:  6     ISSN:  1360-1385     ISO Abbreviation:  Trends Plant Sci.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-04-05     Completed Date:  2001-07-12     Revised Date:  2006-11-20    
Medline Journal Info:
Nlm Unique ID:  9890299     Medline TA:  Trends Plant Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  135-6     Citation Subset:  IM    
Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.
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MeSH Terms
Arabidopsis / genetics*,  metabolism
Arabidopsis Proteins
Cytochrome P-450 Enzyme System / biosynthesis,  genetics,  metabolism
DNA-Binding Proteins / genetics*,  metabolism
Gene Expression Regulation, Plant*
Malates / metabolism
Mixed Function Oxygenases / biosynthesis,  genetics,  metabolism
Phenylpropionates / metabolism
Plant Proteins / genetics*,  metabolism
Proto-Oncogene Proteins c-myb*
Trans-Cinnamate 4-Monooxygenase
Transcription Factors / genetics*,  metabolism
Ultraviolet Rays*
Reg. No./Substance:
0/2-O-sinapoylmalate; 0/ATR1 protein, Arabidopsis; 0/Arabidopsis Proteins; 0/CPC protein, Arabidopsis; 0/DNA-Binding Proteins; 0/Malates; 0/Phenylpropionates; 0/Plant Proteins; 0/Proto-Oncogene Proteins c-myb; 0/Transcription Factors; 9035-51-2/Cytochrome P-450 Enzyme System; EC 1.-/Mixed Function Oxygenases; EC protein, Arabidopsis; EC 4-Monooxygenase

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