Document Detail

Asynchronous development of two monoclonal proteins (IgM lambda and delta 1 chains) in a patient with abdominal lymphoma.
MedLine Citation:
PMID:  404029     Owner:  NLM     Status:  MEDLINE    
An IgM paraprotein was detected in a patient with abdominal lymphoma. Due to some doubts about the malignant nature of the situation, no cytostatic drugs were administered. When seen two years later the patient had considerably deteriorated in clinical status, with evidence of extra-abdominal involvement. At this time he presented a second paraprotein of low of molecular weight (74,000 to 80,000), consisting of two covalently linked delta1-chain fragments.
G Virella; J M Monteiro; M F Lopes-Virella; A Ducla Soares; H H Fudenberg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  39     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-06-30     Completed Date:  1977-06-30     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2247-53     Citation Subset:  AIM; IM    
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MeSH Terms
Abdominal Neoplasms / immunology*
Heavy Chain Disease / immunology*
Immunoglobulin Heavy Chains / biosynthesis*
Immunoglobulin Light Chains / biosynthesis*
Immunoglobulin M / biosynthesis*
Immunoglobulin delta-Chains / biosynthesis*
Immunoglobulin lambda-Chains / biosynthesis*
Lymphoma / immunology*
Molecular Weight
Paraproteins / biosynthesis*
Time Factors
Reg. No./Substance:
0/Immunoglobulin Heavy Chains; 0/Immunoglobulin Light Chains; 0/Immunoglobulin M; 0/Immunoglobulin delta-Chains; 0/Immunoglobulin lambda-Chains; 0/Paraproteins

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