Document Detail

Asymptomatic reopening of ductus arteriosus after successful closure by indomethacin in premature infants.
MedLine Citation:
PMID:  8237357     Owner:  NLM     Status:  MEDLINE    
Indomethacin has been demonstrated to be effective for closure of hemodynamically symptomatic patent ductus arteriosus (PDA) in premature infants. The five cases in this study had acquired asymptomatic reopening of PDA a long time after successful closure by oral indomethacin. Providing adequate oxygen, giving another course of indomethacin, preventing excessive fluid intake and keeping hematocrit level greater than 40% had been tried to close the ducti but all in vain. However, most could be expected to close spontaneously later. Herein, the possible contributing factors and the treatment rationale are discussed.
S L Yen; R J Teng; M M Ho
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui     Volume:  34     ISSN:  0001-6578     ISO Abbreviation:  Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi     Publication Date:    1993 Sep-Oct
Date Detail:
Created Date:  1993-12-09     Completed Date:  1993-12-09     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  16210470R     Medline TA:  Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  379-84     Citation Subset:  IM    
Department of Pediatrics, Taiwan Provincial Tao-Yuan General Hospital, R.O.C.
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MeSH Terms
Ductus Arteriosus, Patent / drug therapy*,  etiology
Indomethacin / therapeutic use*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / drug therapy*,  etiology
Reg. No./Substance:

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