Document Detail


Asymptomatic carotid murmur: ultrasonic factors influencing outcome.
MedLine Citation:
PMID:  3300839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixty consecutive patients with an asymptomatic mid-cervical murmur on auscultation were identified amongst 1000 patients who underwent duplex scanning of the extracranial carotid arteries during 1981-83. They were classified according to the scan results into 12 high risk subjects with greater than 75 per cent stenosis of an internal carotid artery, 37 low risk subjects with a less than 75 per cent stenosis and 6 with no detectable stenosis. The mean duration of follow-up was 3 years (minimum 2 years) or until stroke or death. One was lost to follow-up and four were excluded having undergone carotid endarterectomy during the study. Six of twelve subjects with greater than 75 per cent stenosis suffered a stroke (five fatal and one non-fatal). There were no premonitory signs except in one patient with non-focal cerebral ischaemia for 2 months before an hemispheric stroke. There was one fatal stroke in the less than 75 per cent stenosis group and none in the control group. In all, 17 (28 per cent) patients died (myocardial infarction, 8; stroke, 6; malignant disease, 3). These results confirm that asymptomatic carotid murmurs are associated with increased mortality with most having non-severe carotid disease on duplex scanning and few strokes during follow-up. There is an important minority with tight carotid stenosis who carry a worrying risk of stroke if left untreated.
Authors:
M I Aldoori; G L Benveniste; R N Baird; M Horrocks; J Fairgrieve
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  74     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-09-03     Completed Date:  1987-09-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  496-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Arterial Occlusive Diseases / complications,  diagnosis,  surgery
Carotid Artery Diseases / complications,  diagnosis*,  surgery
Cerebrovascular Disorders / etiology
Endarterectomy
Female
Humans
Male
Middle Aged
Prognosis
Ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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