Document Detail


Asymptomatic autoimmune thyroiditis and coronary heart-disease. Cross-sectional and prospective studies.
MedLine Citation:
PMID:  69779     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cross sectional and prospective surveys of thyroid autoimmunity have been performed in two cohorts of men, 280 living in west Finland and 269 in east Finland. In both populations, aged 50 to 69 years at the first survey, risk factors for coronary heart-disease (C.H.D.) were common. The incidence of C.H.D. was shown to be related to the presence of thyroid antibodies. The results of the cross-sectional studies were not conclusive. The five-year follow-up study emphasised that in both areas asymptomatic thyroid autoimmunity, independently of other known risk factors, was a predictor of subsequent development of C.H.D. The importance of asymptomatic autoimmune thyroid-itis as a risk factor for C.H.D. increases with age.
Authors:
P A Bastenie; L Vanhaelst; J Golstein; P Smets
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-09-22     Completed Date:  1977-09-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  155-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Autoantibodies / isolation & purification
Autoimmune Diseases / complications*
Cholesterol / blood
Coronary Disease / etiology*,  immunology
Cross-Sectional Studies
Finland
Humans
Male
Middle Aged
Prospective Studies
Risk
Thyroid Gland / immunology
Thyroiditis / complications*
Yugoslavia
Chemical
Reg. No./Substance:
0/Autoantibodies; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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