| Asymptomatic low ankle-brachial index in vascular surgery patients: a predictor of perioperative myocardial damage. | |
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MedLine Citation:
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PMID: 19815432 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This study evaluated the prognostic value of asymptomatic low ankle-brachial index (ABI) to predict perioperative myocardial damage, incremental to conventional cardiac risk factors imbedded in cardiac risk indices (Revised Cardiac index and Adapted Lee index). MATERIALS AND METHODS: Preoperative ABI measurements were performed in 627 consecutive vascular surgery patients (carotid artery or abdominal aortic aneurysm repair). An ABI<0.90 was considered abnormal. Patients with ABI>1.40 or (a history of) intermittent claudication were excluded. Serial troponin-T measurements were performed routinely before and after surgery. The main study endpoint was perioperative myocardial damage, the composite of myocardial ischaemia and infarction. Multivariate regression analyses, adjusted for conventional risk factors, evaluated the relation between asymptomatic low ABI and perioperative myocardial damage. RESULTS: In total, 148 (23%) patients had asymptomatic low ABI (mean 0.73, standard deviation+/-0.13). Perioperative myocardial damage was recorded in 107 (18%) patients. Multivariate regression analyses demonstrated that asymptomatic low ABI was associated with an increased risk of perioperative myocardial damage (odds ratio (OR): 2.4, 95% CI: 1.4-4.2) Conclusions: This study demonstrated that asymptomatic low ABI has a prognostic value to predict perioperative myocardial damage in vascular surgery patients, incremental to risk factors imbedded in conventional cardiac risk indices. |
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Authors:
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W-J Flu; J-P van Kuijk; M T Vo?te; R Kuiper; H J M Verhagen; J J Bax; D Poldermans |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-10-07 |
Journal Detail:
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Title: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery Volume: 39 ISSN: 1532-2165 ISO Abbreviation: Eur J Vasc Endovasc Surg Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-02-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9512728 Medline TA: Eur J Vasc Endovasc Surg Country: England |
Other Details:
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Languages: eng Pagination: 62-9 Citation Subset: IM |
Copyright Information:
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Copyright 2009 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Anesthesiology, Erasmus Medical Center, Rotterdam, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Ankle / blood supply* Aortic Aneurysm, Abdominal / mortality, physiopathology, surgery* Biological Markers / blood Blood Pressure* Brachial Artery / physiopathology* Carotid Stenosis / mortality, physiopathology, surgery* Female Heart Diseases / blood, etiology*, mortality, pathology Humans Kaplan-Meiers Estimate Male Middle Aged Myocardium / metabolism, pathology* Odds Ratio Predictive Value of Tests Prevalence Proportional Hazards Models Risk Assessment Risk Factors Time Factors Treatment Outcome Troponin T / blood Vascular Surgical Procedures / adverse effects*, mortality |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Troponin T |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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