Document Detail


Asymmetry of salivary gland I123 metaiodobenzylguanidine (MIBG) uptake in a patient with cervical neuroblastoma and Horner's syndrome--possible etiologic mechanisms.
MedLine Citation:
PMID:  1508596     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Horner's syndrome may be due to a variety of serious underlying disorders including cervical neuroblastoma. Horner's syndrome results from a unilateral disruption of the sympathetic innervation to the head and neck. We report a patient with cervical neuroblastoma in whom post operative metaiodobenzylguanidine (MIBG) scans showed a striking decrease in uptake in the ipsilateral salivary glands. Since the bio-distribution of I123 metaiodobenzylguanidine in the salivary glands in also dependent on sympathetic innervation, the presence of Horner's syndrome can be reflected in the MIBG scan.
Authors:
E D Sandler; R S Hattner; M T Parisi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric radiology     Volume:  22     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1992  
Date Detail:
Created Date:  1992-09-22     Completed Date:  1992-09-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  225-6     Citation Subset:  IM    
Affiliation:
Department of Pathology and Nuclear Medicine, St. Mary's Hospital, San Francisco, California.
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MeSH Terms
Descriptor/Qualifier:
3-Iodobenzylguanidine
Female
Head and Neck Neoplasms / complications,  diagnosis*,  metabolism
Horner Syndrome / diagnosis*,  etiology,  metabolism
Humans
Infant, Newborn
Iodine Radioisotopes / diagnostic use
Iodobenzenes / diagnostic use*,  pharmacokinetics
Male
Neuroblastoma / complications,  diagnosis*,  metabolism
Salivary Glands / innervation,  metabolism
Chemical
Reg. No./Substance:
0/Iodine Radioisotopes; 0/Iodobenzenes; 77679-27-7/3-Iodobenzylguanidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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