Document Detail

Asymmetry of right ventricular enlargement in response to tricuspid regurgitation.
MedLine Citation:
PMID:  10430758     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Analysis of right ventricular adaptation to tricuspid regurgitation was studied in 10 heart transplant recipients following inadvertent endomyocardial biopsy disruption of the tricuspid apparatus. METHODS AND RESULTS: Echocardiography demonstrated progressive diastolic right ventricular cavity enlargement (19.5+/-5.0 to 30.3+/-5.4 cm(2), P<0.0002), with disproportionate elongation along the midminor axis (3.5+/-0.6 to 5. 0+/-0.5 cm, P<0.001). As the right ventricle remodeled to more spherical (and less elliptical) proportions, the end-diastolic right ventricular midminor axis/long axis ratio increased significantly from 0.52+/-0.10 to 0.68+/-0.07, P<0.005. CONCLUSIONS: Ventricular enlargement due to right ventricular volume overload results in disproportionate dilation along the free wall to septum minor axis.
S I Reynertson; R Kundur; G M Mullen; M R Costanzo; T L McKiernan; E K Louie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  100     ISSN:  1524-4539     ISO Abbreviation:  Circulation     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-08-13     Completed Date:  1999-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  465-7     Citation Subset:  AIM; IM    
Division of Cardiology, Loyola University Medical Center, Maywood, IL USA.
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MeSH Terms
Heart Ventricles / pathology,  physiopathology,  ultrasonography
Hypertrophy, Right Ventricular / etiology*,  physiopathology,  ultrasonography
Middle Aged
Prospective Studies
Tricuspid Valve Insufficiency / complications*,  physiopathology,  ultrasonography

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