Document Detail

Asymmetric syntheses of APTO and AETD: the beta-amino acid fragments within microsclerodermins C, D and E.
MedLine Citation:
PMID:  23379896     Owner:  NLM     Status:  Publisher    
Efficient asymmetric syntheses of APTO and AETD, the highly functionalised beta-amino acid fragments within microsclerodermins C, D and E, are reported. The conjugate addition of lithium (R)-N-benzyl-N-(alpha-methylbenzyl)amide to tert-butyl (E,E)-7-(triisopropylsilyloxy)hepta-2,4-dienoate and in situ enolate oxidation with (-)-camphorsulfonyloxaziridine, diastereoselective dihydroxylation of a 2,3-syn-gamma,delta-unsaturated-alpha-hydroxy-beta-amino ester derivative under Donohoe conditions, and a Julia-Kocieński olefination were used as the key steps.
Stephen G Davies; Ai Matsuno Fletcher; Emma M Foster; James A Lee; Paul M Roberts; James E Thomson
Related Documents :
24987736 - Biodiesel from citrullus colocynthis oil: sulfonic-ionic liquid-catalyzed esterificatio...
24613416 - The central role of chloride in the metabolic acid-base changes in canine parvoviral en...
23610056 - An efficient approach to the securinega alkaloids empowered by cooperative n-heterocycl...
24992216 - Metabolic discrimination of swertia mussotii and swertia chirayita known as "zangyinche...
6841546 - Fluorescence high-performance liquid chromatographic determination of free and conjugat...
12419306 - Docosahexaenoic acid suppresses the activity of peroxisome proliferator-activated recep...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-4
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  -     ISSN:  1520-6904     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Identification of signal transduction pathways involved in the formation of platelet subpopulations ...
Next Document:  Implications of the Crystal Structure of the Ammonia Solvate [Au(NH(3))(2)]Cl·4NH(3).