| Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions. | |
| | |
MedLine Citation:
|
PMID: 22245755 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Esters of proteinogenic amino acids efficiently catalyse the formation of erythrose and threose under potentially prebiotic conditions in the highest yields and enantioselectivities yet reported. Remarkably while esters of (l)-proline yield (l)-tetroses, esters of (l)-leucine, (l)-alanine and (l)-valine generate (d)-tetroses, offering the potential to account for the link between natural (l)-amino acids and natural (d)-sugars. The effect of pH and NaCl on the yields and enantioselectivities was also investigated and was shown to be significant, with the optimal enantioselectivities occurring at pH 7. |
| | |
Authors:
|
Laurence Burroughs; Paul A Clarke; Henrietta Forintos; James A R Gilks; Christopher J Hayes; Matthew E Vale; William Wade; Myriam Zbytniewski |
Related Documents
:
|
20492185 - Efficacy of pressure-assisted thermal processing, in combination with organic acids, ag... 1003285 - Synergistic growth promoting action of l-cysteine and nitrogen upon hymenolepis diminut... 8000535 - Characteristics of helicobacter pylori growth in a defined medium and determination of ... 18852515 - Beneficial effects of fluorescent pseudomonads on seed germination, growth promotion, a... 16663515 - Abscisic acid metabolism by source and sink tissues of sugar beet. 22326565 - Long-term protective effect of surface sealants against erosive wear by intrinsic and e... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-16 |
Journal Detail:
|
Title: Organic & biomolecular chemistry Volume: - ISSN: 1477-0539 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Chemistry, University of York, Heslington, York, North Yorks, UKYO10 5DD. paul.clarke@york.ac.uk. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Potential antifertility agents from plants: A comprehensive review.
Next Document: Endoscopic repair of anterior or middle skull base cerebrospinal fluid leaks after tumour resection.