| Asymmetric synthesis of cyclic cis-beta-amino acid derivatives using sulfinimines and prochiral Weinreb amide enolates. | |
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MedLine Citation:
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PMID: 20462208 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cyclic cis-beta-amino Weinreb amides, valuable building blocks for the asymmetric synthesis of cyclic beta-amino acids derivatives, are readily prepared via ring-closing metathesis of sulfinimine-derived N-sulfinyl beta-amino diene Weinreb amides. These unsaturated cyclic cis-beta-amino Weinreb amides are valuable building blocks for the asymmetric synthesis of cyclic beta-amino acid derivatives. |
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Authors:
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Franklin A Davis; Naresh Theddu |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: The Journal of organic chemistry Volume: 75 ISSN: 1520-6904 ISO Abbreviation: J. Org. Chem. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-28 Completed Date: 2010-09-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: United States |
Other Details:
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Languages: eng Pagination: 3814-20 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA. fdavis@temple.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amides
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chemistry Amino Acids / chemical synthesis*, chemistry Cyclization Imines / chemistry* Sulfonium Compounds / chemistry* |
| Grant Support | |
ID/Acronym/Agency:
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GM57870/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Amides; 0/Amino Acids; 0/Imines; 0/Sulfonium Compounds; 0/sulfinimine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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