| Asymmetric Intermolecular Conjugate Addition of Amino Acid Derivatives via Memory of Chirality: Total Synthesis of Manzacidin A. | |
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MedLine Citation:
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PMID: 23350911 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Asymmetric intermolecular conjugate addition of α-amino acid derivatives with 4 via memory of chirality has been developed. The reactions proceeded in up to 98% ee with retention of configuration at the newly formed tetrasubstituted carbon center when R = Me. The product (R = Me) was transformed into manzacidin A. |
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Authors:
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Tomoyuki Yoshimura; Tomohiko Kinoshita; Hiroyasu Yoshioka; Takeo Kawabata |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-25 |
Journal Detail:
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Title: Organic letters Volume: - ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institute for Chemical Research, Kyoto University , Uji 611-0011, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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