Document Detail

Astroglial reactions in periventricular white matter of maturing human brains.
MedLine Citation:
PMID:  9812418     Owner:  NLM     Status:  MEDLINE    
The aim of the study was to examine the astroglial reactivity in brains of fetuses and newborns during the third trimester of gestation. The immuno-histochemical reaction of glial cells with glial fibrillary acidic protein (GFAP) was used. The periventricular white matter damage due to pre- and perinatal hypoxia or sepsis was examined in 11 cases of 28 to 40 weeks of developmental age. Observations of astroglial reaction expressed by the GFAP-positive cells confirmed its sensitivity. The number and hypertrophy of astroglial cells localized in periventricular white matter at parietal level coincide with the predilection of this area to perinatal brain damage.
M Dambska; M Laure-Kamionowska; D Maslińska
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences     Volume:  34     ISSN:  1641-4640     ISO Abbreviation:  Folia Neuropathol     Publication Date:  1996  
Date Detail:
Created Date:  1998-12-14     Completed Date:  1998-12-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9437431     Medline TA:  Folia Neuropathol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  169-72     Citation Subset:  IM    
Laboratory of Developmental Neuropathology, Polish Academy of Sciences, Warszawa.
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MeSH Terms
Astrocytes / pathology*
Brain / pathology*
Cerebral Ventricles / pathology*
Gestational Age
Glial Fibrillary Acidic Protein / diagnostic use
Infant, Newborn
Infant, Premature*
Reg. No./Substance:
0/Glial Fibrillary Acidic Protein

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