| Astrocytes in the developing human brain. An immunohistochemical study. | |
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MedLine Citation:
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PMID: 3766128 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patterns of appearance and maturation of astrocytes, as demonstrated by the immunohistochemical detection of glial fibrillary acidic protein (GFAP), were studied in fetal and mature neonatal brains. Mature astrocytes were present throughout much of the normal central nervous system at 15 weeks of gestation, but they varied in density in different parts. Glioneogenesis continued throughout the fetal and postnatal ages. Marginal glia were conspicuous with strong reaction and probably constituted a distinct subpopulation of glia. There was no temporal relationship between astrocytic proliferation and "myelination gliosis". Radial glia and Bergmann fibers in normal brains did not react to GFAP antiserum. |
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Authors:
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U Roessmann; P Gambetti |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Acta neuropathologica Volume: 70 ISSN: 0001-6322 ISO Abbreviation: Acta Neuropathol. Publication Date: 1986 |
Date Detail:
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Created Date: 1986-11-13 Completed Date: 1986-11-13 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0412041 Medline TA: Acta Neuropathol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 308-13 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Astrocytes
/
analysis,
physiology* Brain / embryology*, growth & development, physiology Embryonic and Fetal Development* Gestational Age Glial Fibrillary Acidic Protein / analysis, physiology Histocytochemistry Humans Infant Infant, Newborn Myelin Sheath / physiology |
| Grant Support | |
ID/Acronym/Agency:
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NS 06239/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Glial Fibrillary Acidic Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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