Document Detail


Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop.
MedLine Citation:
PMID:  21872730     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Asthma in the elderly is underdiagnosed and undertreated, and there is a paucity of knowledge on the subject. The National Institute on Aging convened this workshop to identify what is known and what gaps in knowledge remain and suggest research directions needed to improve the understanding and care of asthma in the elderly. Asthma presenting at an advanced age often has similar clinical and physiologic consequences as seen with younger patients, but comorbid illnesses and the psychosocial effects of aging might affect the diagnosis, clinical presentation, and care of asthma in this population. At least 2 phenotypes exist among elderly patients with asthma; those with longstanding asthma have more severe airflow limitation and less complete reversibility than those with late-onset asthma. Many challenges exist in the recognition and treatment of asthma in the elderly. Furthermore, the pathophysiologic mechanisms of asthma in the elderly are likely to be different from those seen in young asthmatic patients, and these differences might influence the clinical course and outcomes of asthma in this population.
Authors:
Nicola A Hanania; Monroe J King; Sidney S Braman; Carol Saltoun; Robert A Wise; Paul Enright; Ann R Falsey; Sameer K Mathur; Joe W Ramsdell; Linda Rogers; David A Stempel; John J Lima; James E Fish; Sandra R Wilson; Cynthia Boyd; Kushang V Patel; Charles G Irvin; Barbara P Yawn; Ethan A Halm; Stephen I Wasserman; Mark F Sands; William B Ershler; Dennis K Ledford;
Publication Detail:
Type:  Congresses; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Journal of allergy and clinical immunology     Volume:  128     ISSN:  1097-6825     ISO Abbreviation:  J. Allergy Clin. Immunol.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-29     Completed Date:  2011-10-24     Revised Date:  2013-07-09    
Medline Journal Info:
Nlm Unique ID:  1275002     Medline TA:  J Allergy Clin Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S4-24     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.
Affiliation:
Section of Pulmonary and Critical Care Medicine, Asthma Clinical Research Center, Baylor College of Medicine, Houston, Tex., USA.
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MeSH Terms
Descriptor/Qualifier:
Age of Onset
Aged
Asthma / epidemiology,  physiopathology*,  psychology,  therapy*
Biomedical Research*
Comorbidity
Frail Elderly
Humans
Immune System / physiopathology
National Institute on Aging (U.S.)*
Phenotype
Population Surveillance
Psychology
Respiratory Tract Diseases / complications
Risk Factors
Severity of Illness Index
Sickness Impact Profile
United States
Grant Support
ID/Acronym/Agency:
K23 AG032910/AG/NIA NIH HHS; R99 AG999999/AG/NIA NIH HHS
Investigator
Investigator/Affiliation:
Monroe James King / ; Nicola A Hanania / ; Sidney S Braman / ; Carol Saltoun / ; Susan G Nayfield / ; Robert A Wise / ; Alexander Auais / ; Jerome A Dempsey / ; Cynthia M Boyd / ; Paul Enright / ; Ellen Brown / ; William B Ershler / ; Carlos A Camargo / ; Ann Regina Falsey / ; James E Fish / ; Carlos A Vaz Fragoso / ; Paul Garbe / ; Janet Holbrook / ; Lydia Gilbert-McClain / ; Charles G Irvin / ; Ethan A Halm / ; Dennis K Ledford / ; Robert G Hamilton / ; Charlene Levine / ; Sameer K Mathur / ; John J Lima / ; Jeanne Moorman / ; Katherine Pruitt /
Comments/Corrections

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