Document Detail


Asthma and allergic inflammation.
MedLine Citation:
PMID:  20303868     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of these chronic inflammatory disorders.
Authors:
Richard M Locksley
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cell     Volume:  140     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-22     Completed Date:  2010-04-05     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  777-83     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Inc. All rights reserved.
Affiliation:
Howard Hughes Medical Institute, University of California at San Francisco, 94143, USA. locksley@medicine.ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Asthma / epidemiology,  immunology*
Humans
Immunity, Innate
Respiratory Hypersensitivity / epidemiology,  immunology*
Respiratory Mucosa / immunology*
Grant Support
ID/Acronym/Agency:
R01 AI030663-19/AI/NIAID NIH HHS; R01 AI030663-21/AI/NIAID NIH HHS; R37 AI026918-22/AI/NIAID NIH HHS; R37 AI026918-24/AI/NIAID NIH HHS; U19 AI077439/AI/NIAID NIH HHS; U19 AI077439-04/AI/NIAID NIH HHS; //Howard Hughes Medical Institute; //Howard Hughes Medical Institute
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