Document Detail


Associations of weight loss and changes in fat distribution with the remission of hypertension in a bi-ethnic cohort: the Atherosclerosis Risk in Communities Study.
MedLine Citation:
PMID:  12634024     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: To examine associations of weight loss and changes in fat distribution with changes in blood pressure and the remission of hypertension in a community-based sample. METHODS: Participants were 3245 white and African-American men and women, 45-64 years of age, who participated in the Atherosclerosis Risk in Communities Study over an average of 9 years. Mixed models analyses were used to examine the associations of weight loss and changes in fat distribution with changes in blood pressure. Proportional hazard models with time-dependent covariates were used to examine the associations of weight loss and changes in fat distribution with the remission of hypertension. RESULTS: Weight loss was associated with a decrease in systolic blood pressure and diastolic blood pressure and with an increased rate of remission of hypertension. Hazard ratios of the remission of hypertension associated with 1-kg increment in annual weight loss were 2.04 (95% confidence interval [CI]: 1.62-2.59), 1.38 (95% CI: 1.14-1.67), 1.84 (95% CI: 1.47-2.29), and 1.53 (95% CI: 1.14-2.05) for white women, African-American women, white men, and African-American men, respectively. Changes in fat distribution were associated with the remission of hypertension in younger (45-54 years) participants. CONCLUSIONS: Weight loss was associated with a decrease in blood pressure and with remission of hypertension in white and African-American men and women.
Authors:
Juhaeri; June Stevens; L E Chambless; F J Nieto; Daniel Jones; Pamela Schreiner; Donna Arnett; Jianwen Cai
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Preventive medicine     Volume:  36     ISSN:  0091-7435     ISO Abbreviation:  Prev Med     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-13     Completed Date:  2003-07-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0322116     Medline TA:  Prev Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  330-9     Citation Subset:  IM    
Affiliation:
Department of Epidemiology, School of Public Health, CB# 7400 McGavran-Greenberg Hall, University of North Carolina Chapel Hill, 27599-740, USA. juhaeri@email.unc.edu
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MeSH Terms
Descriptor/Qualifier:
African Americans / statistics & numerical data*
Age Distribution
Arteriosclerosis / epidemiology*,  prevention & control
Body Composition*
Body Mass Index
Cohort Studies
Comorbidity
Confidence Intervals
European Continental Ancestry Group / statistics & numerical data*
Female
Humans
Hypertension / epidemiology*,  prevention & control
Incidence
Male
Middle Aged
Obesity / ethnology*,  prevention & control*
Primary Prevention / organization & administration*
Proportional Hazards Models
Retrospective Studies
Risk Factors
Sex Distribution
United States / epidemiology
Weight Loss*
Grant Support
ID/Acronym/Agency:
N01-HC-55015/HC/NHLBI NIH HHS; N01-HC-55016/HC/NHLBI NIH HHS; N01-HC-55018/HC/NHLBI NIH HHS; N01-HC-55019/HC/NHLBI NIH HHS; N01-HC-55020/HC/NHLBI NIH HHS; N01-HC-55021/HC/NHLBI NIH HHS; N01-HC-55022/HC/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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