Document Detail


Associations of methylmercury and inorganic mercury between human cord blood and maternal blood: A meta-analysis and its application.
MedLine Citation:
PMID:  24792881     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Considering the different ability of placental transfer, an assessment of the cord:maternal blood ratio for both methylmercury (MeHg) and inorganic mercury (IHg) is needed especially for interpreting the low-level prenatal exposure. In this study, we conducted a Monte Carlo-based meta-analysis to comprehensively estimate that ratio for MeHg (RMeHg) and IHg (RIHg). The obtained values followed log-normal distributions, with a mean (standard deviation) of 1.89 (0.98) and 1.01 (0.55) for RMeHg and RIHg, respectively. We also estimated the percentage of MeHg in the blood by means of THg in cord and maternal blood using the RMeHg and RIHg, and obtained a value very close to the measured one (relative deviation, -0.4%). In conclusion, the fetus is exposed to approximately twice as much MeHg and to the same level of IHg as in maternal blood; the introduced model provides a rough but reasonable estimate of the percentage of MeHg in the blood.
Authors:
Langbo Ou; Long Chen; Cen Chen; Tianjun Yang; Huanghuang Wang; Yindong Tong; Dan Hu; Wei Zhang; Wenjing Long; Xuejun Wang
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-29
Journal Detail:
Title:  Environmental pollution (Barking, Essex : 1987)     Volume:  191C     ISSN:  1873-6424     ISO Abbreviation:  Environ. Pollut.     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-5-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804476     Medline TA:  Environ Pollut     Country:  -    
Other Details:
Languages:  ENG     Pagination:  25-30     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Ltd. All rights reserved.
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