Document Detail

Associations of intake of antioxidant vitamins and fatty acids with asthma in pre-school children.
MedLine Citation:
PMID:  23021626     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Increasing childhood asthma rates may be due to changing dietary lifestyle. We investigated the association of dietary intake of antioxidant vitamins and fatty acids with asthma in Japanese pre-school children. DESIGN: Cross-sectional study. SETTING: School-based survey on lifestyle/diet and health status in children in Japan. SUBJECTS: Parents of 452 children aged 3-6 years completed a questionnaire on the children's and parents' lifestyle and demographics. Children were classified into asthma cases and non-asthma cases in accordance with the ATS-DLD (American Thoracic Society and Division of Lung Diseases of the National Heart, Lung, and Blood Institute) questionnaire. Children's diet was assessed using a 3 d dietary record completed by parents. Children's age, sex, BMI, history of food allergy, maternal age, parental history of allergy, maternal education, family size and second-hand smoking were included as covariates. Logistic regression models were used to examine the association between children's diet and asthma. RESULTS: Compared with children with the lowest intake tertile for vitamin C and vitamin E, those in the highest were significantly inversely associated with asthma; adjusted OR (95 % CI) were 0·35 (0·14, 0·88) and 0·32 (0·12, 0·85), respectively. A statistically significant trend was also observed. Fruit intake showed an inverse but insignificant association with asthma. There were no associations of any type of fatty acids with asthma. CONCLUSIONS: These data suggest that children with high intakes of vitamins C and E may be associated with a reduced prevalence of asthma.
Kozue Nakamura; Keiko Wada; Yukari Sahashi; Yuya Tamai; Michiko Tsuji; Kaori Watanabe; Sakiko Ohtsuchi; Kyoko Ando; Chisato Nagata
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-1
Journal Detail:
Title:  Public health nutrition     Volume:  -     ISSN:  1475-2727     ISO Abbreviation:  Public Health Nutr     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808463     Medline TA:  Public Health Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-6     Citation Subset:  -    
1 Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido Gifu 501-1194, Japan.
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