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Associations between vitamin D status in infants and blood lipids, body mass index and waist circumference.
MedLine Citation:
PMID:  21418102     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aim:  To study the relationships between 25-hydroxyvitamin D status and blood lipids, insulin, glucose, body mass index and waist circumference in infants. Methods:  In a cross sectional study, 255 infants aged 9 months with a blood sample for 25-hydroxyvitamin D were examined. Plasma 25-hydroxyvitamin D concentrations were analysed by chemiluminescent immunoassay. Associations between plasma 25-hydroxyvitamin D and high density lipoprotein, low density lipoprotein, total cholesterol, triglycerides, insulin, glucose, body mass index and waist circumference were analysed. Results:  Mean plasma 25-hydroxyvitamin D was 77.2 ± 22.7 nmol/L. At the time of examination, 97% received vitamin D supplementation. 25-hydroxyvitamin D was negatively associated with high density lipoprotein (P=0.003), cholesterol (P=0.002) and triglycerides (P=0.010) in multivariate analysis controlled for gender, season, body mass index, length, birth weight and breastfeeding. There were no associations between 25-hydroxyvitamin D and glucose or insulin (all P>0.05). 25-hydroxyvitamin D was negatively associated with body mass index (P=0.005) and waist circumference (P=0.002) controlled for gender, season, breastfeeding, birth weight and length. Conclusion:  Vitamin D status is negatively associated with blood lipids, body mass index and waist circumference in infants where nearly all received vitamin D supplements. Whether this has long term health effects remains to be elucidated.
Authors:
K Arnberg; M Ostergård; Al Madsen; H Krarup; Kf Michaelsen; C Mølgaard
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-18
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Affiliation:
Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark Department of Clinical Biochemistry, Aalborg Hospital, Denmark.
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