| Associations between vitamin D status in infants and blood lipids, body mass index and waist circumference. | |
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MedLine Citation:
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PMID: 21418102 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aim: To study the relationships between 25-hydroxyvitamin D status and blood lipids, insulin, glucose, body mass index and waist circumference in infants. Methods: In a cross sectional study, 255 infants aged 9 months with a blood sample for 25-hydroxyvitamin D were examined. Plasma 25-hydroxyvitamin D concentrations were analysed by chemiluminescent immunoassay. Associations between plasma 25-hydroxyvitamin D and high density lipoprotein, low density lipoprotein, total cholesterol, triglycerides, insulin, glucose, body mass index and waist circumference were analysed. Results: Mean plasma 25-hydroxyvitamin D was 77.2 ± 22.7 nmol/L. At the time of examination, 97% received vitamin D supplementation. 25-hydroxyvitamin D was negatively associated with high density lipoprotein (P=0.003), cholesterol (P=0.002) and triglycerides (P=0.010) in multivariate analysis controlled for gender, season, body mass index, length, birth weight and breastfeeding. There were no associations between 25-hydroxyvitamin D and glucose or insulin (all P>0.05). 25-hydroxyvitamin D was negatively associated with body mass index (P=0.005) and waist circumference (P=0.002) controlled for gender, season, breastfeeding, birth weight and length. Conclusion: Vitamin D status is negatively associated with blood lipids, body mass index and waist circumference in infants where nearly all received vitamin D supplements. Whether this has long term health effects remains to be elucidated. |
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Authors:
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K Arnberg; M Ostergård; Al Madsen; H Krarup; Kf Michaelsen; C Mølgaard |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-18 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: - ISSN: 1651-2227 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Acta Paediatrica © 2011 Foundation Acta Paediatrica. |
Affiliation:
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Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark Department of Clinical Biochemistry, Aalborg Hospital, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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