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Associations between dietary patterns and arterial stiffness, carotid artery intima-media thickness and atherosclerosis.
MedLine Citation:
PMID:  20431391     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Few studies have examined the association between global diet, assessed through dietary patterns, and arterial structure and function. The aim of this study was to investigate the relationship between carotid-femoral pulse-wave velocity (PWV), common carotid-arteries intima-media thickness (CCA-IMT) and plaques with dietary patterns measured 7.5 years earlier.
DESIGN: A prospective cohort study between diet and markers of structure and function of large arteries.
METHODS: Dietary patterns (linear combination of food consumption) were identified using principal component analysis among 1026 middle-aged participants in the SUpplémentation en VItamines et Minéraux AntioXydants (SU.VI.MAX) vascular substudy. Dietary data were based on repeated 24-h dietary records (at least three records during 2 years) obtained at inclusion. Carotid-femoral PWV was used to assess aortic stiffness. Carotid ultrasound examination included measurements of CCA-IMT and carotid plaques.
RESULTS: Four dietary patterns were identified. In multivariate models, a significant positive association was observed between PWV and a dietary pattern positively correlated with meat and alcohol consumption and negatively correlated with fibers, vitamins B9 and C, β-carotene and calcium consumption. Adjusted PWV mean across tertiles of this pattern score was 11.15, 11.26 and 11.58 m/s in the first, second and third tertiles, respectively (P for trend=0.03). Others dietary patterns were not associated with PWV and we detected no association between dietary patterns and IMT or plaques.
CONCLUSION: This study suggests that a nutritionally poor dietary pattern, characterized by a high meat and alcohol consumption and low micronutrients intake, is related to an increased stiffening of large arteries.
Authors:
Emmanuelle Kesse-Guyot; Anne-Claire Vergnaud; Léopold Fezeu; Mahmoud Zureik; Jacques Blacher; Sandrine Péneau; Serge Hercberg; Pilar Galan; Sébastien Czernichow
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology     Volume:  17     ISSN:  1741-8275     ISO Abbreviation:  Eur J Cardiovasc Prev Rehabil     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-01-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101192000     Medline TA:  Eur J Cardiovasc Prev Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  718-24     Citation Subset:  IM    
Affiliation:
UMR, INSERM U557/INRA U1125/CNAM/Université Paris 13, CRNH-IdF, Bobigny, France.
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