Document Detail


Associations of alcohol consumption with clinical and MRI measures in multiple sclerosis.
MedLine Citation:
PMID:  22650167     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
While the harmful effects of alcohol abuse are well documented, experimental and clinical data support a potential benefit of light to moderate alcohol consumption. Cross-sectional studies have suggested an association between alcohol consumption and multiple sclerosis (MS) disability. In the absence of prospective, longitudinal studies, the causal nature of this relationship cannot be established. It remains possible that patients with increased disability progression reduce their alcohol intake. Even though there is substantial evidence for anti-inflammatory effects of low-to-moderate doses of alcohol, the associations need to be interpreted very cautiously. This study discusses the current state of knowledge about MS and alcohol consumption, and the limitations in conducting research with retrospective data in patients with MS.
Authors:
Marie B D'hooghe; Jacques De Keyser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of neurotherapeutics     Volume:  12     ISSN:  1744-8360     ISO Abbreviation:  Expert Rev Neurother     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101129944     Medline TA:  Expert Rev Neurother     Country:  England    
Other Details:
Languages:  eng     Pagination:  657-60     Citation Subset:  IM    
Affiliation:
National Multiple Sclerosis Center, Melsbroek, Belgium. marie.dhooghe@mscenter.be.
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