Document Detail

Associations between peripheral artery disease and ischemic stroke: implications for primary and secondary prevention.
MedLine Citation:
PMID:  20689082     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Although peripheral artery disease (PAD) has a particularly poor prognosis compared with vascular disease in other territories, little attention is paid to its epidemiology, treatment, and prevention. Despite the high prevalence of PAD in patients with stroke, and of stroke in patients with PAD, PAD is omitted from all guidelines for treatment, prevention, and rehabilitation of stroke, although coronary artery disease risk is considered. Therefore, routine PAD screening is seldom undertaken and so disease is probably often missed. Summary of Review- This review evaluates epidemiology of PAD in patients with stroke and of stroke in patients with PAD. The role of the ankle-brachial pressure index; imaging and novel markers in risk prediction of PAD in patients with stroke; and treatment and prevention of PAD are reviewed.
CONCLUSIONS: In both primary and secondary prevention settings, PAD indicates a high risk of future events. Data on which additional preventive measures are beneficial in this patient group are lacking, but the presence of PAD does have implications for current management in both primary and secondary prevention of stroke.
Amitava Banerjee; F Gerald Fowkes; Peter M Rothwell
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-08-05
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  41     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-31     Completed Date:  2010-09-22     Revised Date:  2013-08-12    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2102-7     Citation Subset:  IM    
Stroke Prevention Research Unit, University of Oxford, Oxford, UK.
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MeSH Terms
Ankle Brachial Index
Brain Ischemia / epidemiology*,  prevention & control
Peripheral Vascular Diseases / epidemiology*
Secondary Prevention
Stroke / epidemiology*,  prevention & control
Grant Support
G0500987//Medical Research Council; OSRP2/1006//The Dunhill Medical Trust; RP-PG-0606-1146//Department of Health; //Medical Research Council

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