Document Detail

Association study of the HLA-A2 allele in Italian Alzheimer disease patients.
MedLine Citation:
PMID:  18359130     Owner:  NLM     Status:  MEDLINE    
Association of the A2 allele of the human leukocyte antigen (HLA) with Alzheimer disease (AD) is still controversial. The authors evaluated HLA-A2 association with AD in 173 Italian AD patients, considering also the possible interaction with APOE pattern, age of onset and gender. No evidence of any association was found.
Franca Rosa Guerini; Elena Calabrese; Cristina Agliardi; Milena Zanzottera; Massimo Franceschi; Luigi Maria Edoardo Grimaldi; Raffaello Nemni; Pasquale Ferrante
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-03-21
Journal Detail:
Title:  Neurobiology of aging     Volume:  30     ISSN:  1558-1497     ISO Abbreviation:  Neurobiol. Aging     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-10-19     Completed Date:  2010-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100437     Medline TA:  Neurobiol Aging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2082-3     Citation Subset:  IM    
Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation IRCCS, Milan, Italy.
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MeSH Terms
Age of Onset
Alzheimer Disease / epidemiology,  genetics*
Apolipoprotein E4 / genetics
Genetic Association Studies
HLA-A2 Antigen / genetics*
Italy / epidemiology
Middle Aged
Sequence Analysis, DNA
Sex Factors
Reg. No./Substance:
0/Apolipoprotein E4; 0/HLA-A2 Antigen

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