Document Detail


Association study of the HLA-A2 allele in Italian Alzheimer disease patients.
MedLine Citation:
PMID:  18359130     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Association of the A2 allele of the human leukocyte antigen (HLA) with Alzheimer disease (AD) is still controversial. The authors evaluated HLA-A2 association with AD in 173 Italian AD patients, considering also the possible interaction with APOE pattern, age of onset and gender. No evidence of any association was found.
Authors:
Franca Rosa Guerini; Elena Calabrese; Cristina Agliardi; Milena Zanzottera; Massimo Franceschi; Luigi Maria Edoardo Grimaldi; Raffaello Nemni; Pasquale Ferrante
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-03-21
Journal Detail:
Title:  Neurobiology of aging     Volume:  30     ISSN:  1558-1497     ISO Abbreviation:  Neurobiol. Aging     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-10-19     Completed Date:  2010-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100437     Medline TA:  Neurobiol Aging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2082-3     Citation Subset:  IM    
Affiliation:
Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation IRCCS, Milan, Italy. fguerini@dongnocchi.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Age of Onset
Aged
Alleles
Alzheimer Disease / epidemiology,  genetics*
Apolipoprotein E4 / genetics
Female
Genetic Association Studies
Genotype
HLA-A2 Antigen / genetics*
Humans
Italy / epidemiology
Male
Middle Aged
Phenotype
Sequence Analysis, DNA
Sex Factors
Chemical
Reg. No./Substance:
0/Apolipoprotein E4; 0/HLA-A2 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Fear of animal foods: a century of zoonotics.
Next Document:  Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow di...