Document Detail

Association of sinus node dysfunction, atrioventricular node conduction abnormality and ventricular arrhythmia in patients with Kawasaki disease and coronary involvement.
MedLine Citation:
PMID:  18219166     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This study was performed to investigate the incidence of arrhythmias in patients with Kawasaki disease (KD). METHODS AND RESULTS: Electrophysiologic studies (EPS) were performed in 40 patients (mean age: 10.3+/-5.1 years; 30 males, 10 females) with KD who had severe to moderate coronary artery disease. Clinical arrhythmias were documented in 4 patients (premature ventricular contractions, ventricular tachycardia, atrioventricular block, and ventricular fibrillation). Dual atrioventricular nodal pathways were demonstrated in 3 patients. Nonsustained atrial fibrillation was induced in 1 patient. The AH interval was prolonged in 2 patients. The Wenckebach rate was 164+/-37 beats/min, and 4 of the patients had a decreased Wenckebach rate. The maximum and corrected sinus node recovery times were 997+/-257 ms and 281+/-130 ms, respectively, and 7 patients were thought to be abnormal. The sino-atrial conduction time was 108+/-64 ms, and 2 patients had prolonged conduction times. CONCLUSIONS: Although there was no relationship between coronary stenosis or obstruction and the EPS parameters, the incidence of abnormal sinus node and atrioventricular node function is apparently higher in KD patients than in the normal population. These functional abnormalities may possibly be caused by myocarditis or an abnormal microcirculation in the sinus node and atrioventricular node artery. In some patients, myocardial ischemia may provoke malignant ventricular arrhythmia.
Naokata Sumitomo; Kensuke Karasawa; Kazuo Taniguchi; Rie Ichikawa; Junji Fukuhara; Osamu Abe; Michio Miyashita; Hiroshi Kanamaru; Mamoru Ayusawa; Kensuke Harada
Related Documents :
6188116 - Atrioventricular and ventriculo-atrial conduction in patients with symptomatic sinus no...
6204296 - Double ventricular pacing in a patient with a "ddd" universal pacemaker.
17619666 - Pacemaker therapies in cardiology.
6160496 - A search for modulation in intermittent ventricular parasystole.
11711686 - Managing ambulatory anticoagulation.
20798256 - Detection of peripheral artery disease by duplex ultrasonography among hemodialysis pat...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  72     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-25     Completed Date:  2008-05-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  274-80     Citation Subset:  IM    
Department of Pediatrics and Pediatric Health, Nihon University School of Medicine, 30-1Oyaguchi Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arrhythmias, Cardiac / etiology*,  physiopathology
Atrioventricular Block / etiology,  physiopathology
Atrioventricular Node / physiopathology*
Child, Preschool
Coronary Artery Disease / complications*,  physiopathology
Coronary Circulation
Microcirculation / physiopathology
Mucocutaneous Lymph Node Syndrome / complications*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Role of electrophysiologic study (EPS)-guided preventive therapy for the management of ventricular t...
Next Document:  Efficacy of pulmonary vein isolation in paroxysmal atrial fibrillation patients with a Brugada elect...