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Association of serum uric Acid with level of blood pressure in type 2 diabetic patients.
MedLine Citation:
PMID:  24685739     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This study was conducted to investigate the association between serum uric acid level and blood pressure in type 2 diabetes mellitus. Sixty patients with type 2 diabetes mellitus were enrolled to the study. None of the patients had a history of gout, were treated with allopurinol, or were treated with antihypertensive drugs previously. The mean duration of DM was 9.2 ± 4.9 years. The mean serum creatinine level was 0.98 +/- 0.22 mg/dL, and the mean serum UA level was 4.4 +/- 1.2 mg/dL. The mean protein level in 24-hour urine sample was 388 +/- 22 mg/d. The mean systolic and diastolic blood pressure values were 133.0 +/- 13.0 mm Hg and 84.0 +/- 7.4 mm Hg, respectively. There was no significant difference in levels of serum uric acid, hemoglobin A1c, serum creatinine, proteinuria, or systolic and diastolic pressure between the men and the women. A significant positive correlation was seen between serum UA and systolic (r = 0.312, P = .02) and diastolic blood pressure (r = 0.297, P = .03). Results of this study suggest that serum uric acid had a strong association with levels of systolic and diastolic blood pressure in type 2 diabetic patients. More attention to the serum uric acid level and treatment of hyperuricemia could halt the progress of diabetic nephropathy.
Authors:
Mahmoud Rafieian-Kopaei; Saeed Behradmanesh; Soleiman Kheiri; Hamid Nasri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Iranian journal of kidney diseases     Volume:  8     ISSN:  1735-8604     ISO Abbreviation:  Iran J Kidney Dis     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-04-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101316967     Medline TA:  Iran J Kidney Dis     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  152-4     Citation Subset:  IM    
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