| Association of serum uric Acid with level of blood pressure in type 2 diabetic patients. | |
MedLine Citation:
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PMID: 24685739 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This study was conducted to investigate the association between serum uric acid level and blood pressure in type 2 diabetes mellitus. Sixty patients with type 2 diabetes mellitus were enrolled to the study. None of the patients had a history of gout, were treated with allopurinol, or were treated with antihypertensive drugs previously. The mean duration of DM was 9.2 ± 4.9 years. The mean serum creatinine level was 0.98 +/- 0.22 mg/dL, and the mean serum UA level was 4.4 +/- 1.2 mg/dL. The mean protein level in 24-hour urine sample was 388 +/- 22 mg/d. The mean systolic and diastolic blood pressure values were 133.0 +/- 13.0 mm Hg and 84.0 +/- 7.4 mm Hg, respectively. There was no significant difference in levels of serum uric acid, hemoglobin A1c, serum creatinine, proteinuria, or systolic and diastolic pressure between the men and the women. A significant positive correlation was seen between serum UA and systolic (r = 0.312, P = .02) and diastolic blood pressure (r = 0.297, P = .03). Results of this study suggest that serum uric acid had a strong association with levels of systolic and diastolic blood pressure in type 2 diabetic patients. More attention to the serum uric acid level and treatment of hyperuricemia could halt the progress of diabetic nephropathy. |
Authors:
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Mahmoud Rafieian-Kopaei; Saeed Behradmanesh; Soleiman Kheiri; Hamid Nasri |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Iranian journal of kidney diseases Volume: 8 ISSN: 1735-8604 ISO Abbreviation: Iran J Kidney Dis Publication Date: 2014 Mar |
Date Detail:
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Created Date: 2014-04-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101316967 Medline TA: Iran J Kidney Dis Country: Iran |
Other Details:
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Languages: eng Pagination: 152-4 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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