Document Detail

Association of serum C-reactive protein and LDL:HDL with myocardial infarction.
MedLine Citation:
PMID:  16900713     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To identify frequency of the following markers of atherosclerosis risk: high C-Reactive Protein (CRP) and ratio between serum levels of low density lipoprotein (LDL) and high density lipoprotein (HDL) and to determine the association of high serum CRP levels and LDL:HDL in the patients presenting at NICVD with first myocardial infarction. METHODS: This case control study was conducted at National Institute for Cardiovascular Disease (NICVD), in Karachi, comprising of 50 male patients of acute myocardial infarction (without any other co-morbidity) and 50 matching controls. RESULTS: In this study, CRP levels were significantly high (p = 0.003) and serum HDL levels significantly low (p = 0.006) in patients as compared to controls. Serum LDL levels and the ratio of LDL and HDL were not significantly different among the two groups. CONCLUSION: High serum CRP levels rather than high LDL:HDL are associated with myocardial infarction in the patients presenting at NICVD with first myocardial infarction.
Bibi Kulsoom; S Hasnain Nazrul
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  56     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-08-11     Completed Date:  2006-11-27     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  318-22     Citation Subset:  IM    
Department of Biochemistry, Ziauddin Medical University and Hospital, Karachi.
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MeSH Terms
C-Reactive Protein / analysis*
Cholesterol, HDL / blood*
Cholesterol, LDL / blood*
Middle Aged
Myocardial Infarction / blood*,  diagnosis*
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 9007-41-4/C-Reactive Protein

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