Document Detail

Association of plasma osteoprotegerin levels with stroke severity and functional outcome in acute ischaemic stroke patients.
MedLine Citation:
PMID:  23030274     Owner:  NLM     Status:  Publisher    
Osteoprotegerin (OPG) is known to regulate processes involved in vascular injury and inflammation. We investigated the relationship between plasma OPG levels and stroke subtype, stroke severity at admission and functional outcome at 3 months in 172 patients with acute ischaemic stroke. Patients with large artery atherosclerosis and those with multiple causes had higher plasma OPG levels than patients with lacune. Increased plasma OPG levels were independently associated with more severe stroke and poor functional outcome. These results suggest pleiotropic roles of OPG in mediating atherosclerosis and ischaemic brain injury. OPG is a potential biomarker for predicting neurologic outcome in stroke.
Tae-Jin Song; Jinkwon Kim; Seung-Hee Yang; Ji Hye Park; Hye Sun Lee; Chung Mo Nam; Ok-Hee Lee; Young Dae Kim; Hyo Suk Nam; Ji Hoe Heo
Related Documents :
20002564 - Chemerin, vaspin and insulin resistance in chronic hepatitis c.
18697874 - Plasma adiponectin for prediction of cardiovascular events and mortality in high-risk p...
12880724 - Plasma leptin levels in patients with burn injury: a preliminary report.
12471304 - Plasma organochlorine concentrations in endurance athletes and obese individuals.
9334854 - Effects of hcg and beta-hcg on il-2 and sil-2r secretion from human peripheral blood mo...
6722244 - Production and characterization of monoclonal antibodies to the sperm acrosome stabiliz...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-3
Journal Detail:
Title:  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals     Volume:  -     ISSN:  1366-5804     ISO Abbreviation:  Biomarkers     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606000     Medline TA:  Biomarkers     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Neurology, Yonsei University College of Medicine , Seoul , Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Detection of superoxide radicals in tomato plants exposed to salinity, drought, cold and heavy metal...
Next Document:  The Mechanism and Kinetics for Ammonium Dinitramide (ADN) Sublimation: A First-Principles Study.