Document Detail

Association of paternal alcohol use with gestational age and birth weight.
MedLine Citation:
PMID:  1462251     Owner:  NLM     Status:  MEDLINE    
Paternal alcohol use has been associated with a number of adverse reproductive outcomes in laboratory animals and there is one epidemiologic report of a detrimental effect on infant birth weight. To expand the epidemiologic evidence, data from the Child Health and Development Studies were analyzed. Data collected from the onset of prenatal care in 10,232 women enrolled in the Kaiser Foundation Health Plan and residing in the San Francisco East Bay area between June 1959 and September 1966 were available, including information on the mother's report of paternal alcohol consumption and a number of potential confounders. Pregnancy outcomes included preterm delivery (< 37 weeks completed gestation), moderately low birth weight (1,501-2,500 g), very low birth weight (< or = 1,500 g), small-for-gestational-age (< 10th percentile of weight for gestational age), and mean birth weight. Paternal alcohol use, analyzed in intervals from 0 to 2.0 or more drinks per day, showed no association with any of the outcomes of interest. Adjusted prevalence odds ratios ranged from 0.7 to 1.5, with no indication of a monotonic dose-response gradient. Mean birth weight was also virtually unrelated to paternal alcohol use. Compared with the earlier report, this population had a very modest level of alcohol consumption. Nonetheless, within the range that was studied there appears to be no association between paternal alcohol use and birth outcome.
D A Savitz; J Zhang; P Schwingl; E M John
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Teratology     Volume:  46     ISSN:  0040-3709     ISO Abbreviation:  Teratology     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1993-01-12     Completed Date:  1993-01-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0153257     Medline TA:  Teratology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  465-71     Citation Subset:  IM    
Carolina Population Center, School of Public Health, University of North Carolina, Chapel Hill 27599-7400.
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MeSH Terms
Alcohol Drinking / adverse effects*
Birth Weight*
Epidemiologic Factors
Gestational Age
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age
Pregnancy Outcome / epidemiology*
San Francisco / epidemiology

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