| Association of paternal alcohol use with gestational age and birth weight. | |
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MedLine Citation:
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PMID: 1462251 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Paternal alcohol use has been associated with a number of adverse reproductive outcomes in laboratory animals and there is one epidemiologic report of a detrimental effect on infant birth weight. To expand the epidemiologic evidence, data from the Child Health and Development Studies were analyzed. Data collected from the onset of prenatal care in 10,232 women enrolled in the Kaiser Foundation Health Plan and residing in the San Francisco East Bay area between June 1959 and September 1966 were available, including information on the mother's report of paternal alcohol consumption and a number of potential confounders. Pregnancy outcomes included preterm delivery (< 37 weeks completed gestation), moderately low birth weight (1,501-2,500 g), very low birth weight (< or = 1,500 g), small-for-gestational-age (< 10th percentile of weight for gestational age), and mean birth weight. Paternal alcohol use, analyzed in intervals from 0 to 2.0 or more drinks per day, showed no association with any of the outcomes of interest. Adjusted prevalence odds ratios ranged from 0.7 to 1.5, with no indication of a monotonic dose-response gradient. Mean birth weight was also virtually unrelated to paternal alcohol use. Compared with the earlier report, this population had a very modest level of alcohol consumption. Nonetheless, within the range that was studied there appears to be no association between paternal alcohol use and birth outcome. |
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Authors:
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D A Savitz; J Zhang; P Schwingl; E M John |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Teratology Volume: 46 ISSN: 0040-3709 ISO Abbreviation: Teratology Publication Date: 1992 Nov |
Date Detail:
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Created Date: 1993-01-12 Completed Date: 1993-01-12 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0153257 Medline TA: Teratology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 465-71 Citation Subset: IM |
Affiliation:
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Carolina Population Center, School of Public Health, University of North Carolina, Chapel Hill 27599-7400. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohol Drinking / adverse effects* Birth Weight* Epidemiologic Factors Fathers* Female Gestational Age Humans Infant, Low Birth Weight Infant, Newborn Infant, Premature Infant, Small for Gestational Age Male Pregnancy Pregnancy Outcome / epidemiology* San Francisco / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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