Document Detail


Association of parity with osteoprotegerin levels and atherosclerosis.
MedLine Citation:
PMID:  23287888     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: Association of serum osteoprotegerin (OPG) levels and cardiovascular disorders has been shown previously. The aim of this observational study was to investigate the relationship between parity, OPG and carotid intima-media thickness (CIMT) in premenopausal women. METHODS: A total of 128 women (mean age ± SD, 37.8 ± 4.7 years) were divided into three group according to parity [1-3 as group 1 (n = 41), 4-6 as group 2 (n = 55) and ≥7 as group 3 (n = 32)]. Serum OPG was measured and CIMT was evaluated. RESULTS: Both serum OPG levels and CIMT tended to increase with advancing parity; OPG level was significantly higher in group 3 than in group 1 (p = 0.013) and CIMT was significantly higher in group 2 and group 3 than in group 1 (p < 0.001 for both). In correlation analyses, there were significant correlations between all three parameters. CONCLUSIONS: Our results revealed that there was an increased risk of cardiovascular disease in women with multiparity. Significant association of OPG with CIMT suggested that OPG might play a role in the pathogenesis of parity-induced atherosclerosis.
Authors:
Mehmet Ali Eren; Mehmet Vural; Sema Yildiz; Hasan Cece; Hakan Camuzcuoglu; Harun Toy; Abdurrahim Kocyigit
Related Documents :
23986278 - Pancreatic cancer mortality in serbia from 1991-2010 - a joinpoint analysis.
24819748 - Plasma homocysteine, dietary b vitamins, betaine, and choline and risk of peripheral a...
24631978 - Profile of women detected drink driving via roadside breath testing (rbt) in queensland...
24639438 - Do population-based interventions widen or narrow socioeconomic inequalities? the case ...
6505498 - Epidemiologic designs for the study of acquired immunodeficiency disease: options and o...
9093598 - Outcome after coronary artery surgery in women and men in the north of england.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-4
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  -     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Endocrinology, School of Medicine, Faculty of Medicine, Harran University, Yenisehir Campus, Sanliurfa, 63300, Turkey, drmalieren@hotmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A prospective, case-control study on the lipid profile and the cardiovascular risk of menopausal wom...
Next Document:  Association of clopidogrel pretreatment with mortality, cardiovascular events, and major bleeding am...