Document Detail


Association of military training with oxidative stress and overreaching.
MedLine Citation:
PMID:  21266928     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We hypothesized that increased oxidative stress and disrupted redox balance may be predisposing factors and markers for overreaching (OR). PURPOSE:: To examine whether oxidative stress markers and antioxidant status and physical fitness are related to overreaching during an 8-week military basic training (BT) period. METHODS:: Oxidative stress and antioxidant status were evaluated in the beginning, after 4 and 7 weeks of training in 35 males (age 19.7 ± 0.3 yrs) at rest and immediately after a 45-min submaximal exercise. Physical activity (PA) was monitored by accelerometer throughout BT. Indicators of OR were also examined. RESULTS:: From baseline to wk4 increased daytime moderate to vigorous PA led to concomitant decreases in the ratio oxidized to total glutathione (GSSG/TGSH) and GSSG. After 4 weeks of BT, GSSG/TGSH and GSSG returned to the baseline values at rest, while PA remained unchanged. At every time point acute exercise decreased TGSH and increased GSSG and GSSG/TGSH, while a decrease was observed in antioxidant capacity after 4 weeks of training. In the beginning of BT, OR subjects (11 of the 35 males) had higher GSSG, GSSG/TGSH and malondialdehyde (a marker of lipid peroxidation) at rest (P<0.01-0.05) and lower response of GSSG and GSSG/TGSH ratio (P<0.01) to exercise than noOR subjects. Moreover, OR subjects had higher PA during BT than noOR (P<0.05). CONCLUSION:: The sustained training load during the last four weeks of BT led to oxidative stress observable both at rest and after submaximal exercise. Increased oxidative stress may be a marker of insufficient recovery leading possibly to OR.
Authors:
Minna M Tanskanen; Arja L Uusitalo; Hannu Kinnunen; Keijo Häkkinen; Heikki Kyröläinen; Mustafa Atalay
Related Documents :
1387688 - Does anaerobic threshold correlate with maximal lactate steady-state?
10776898 - Intra- and extra-cellular lactate shuttles.
10751188 - Endurance training, expression, and physiology of ldh, mct1, and mct4 in human skeletal...
20013328 - The relationship between exercise intensity and the sweat lactate excretion rate.
9554618 - Left ventricular-arterial system coupling at peak exercise in dilated nonischemic cardi...
6684028 - Muscle performance, morphology and metabolic capacity during strength training and detr...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-21
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  -     ISSN:  1530-0315     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Department of Biology of Physical Activity, University of Jyväskylä, Finland 2Department of Clinical Physiology and Nuclear Medicine, Helsinki University Hospital, Finland 3Polar Electro Oy, Kempele, Finland 4Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Changes in fMRI cortical activation withcross-education to an immobilized limb.
Next Document:  Effect of caffeine on reactive agility time when fresh and fatigued.